Mario Negri Institute for Pharmacological Research
Laboratory of General Epidemiology
WEB ADDRESS / INDIRIZZO INTERNET

http://www.marionegri.it/LAB=53
TEAM LEADER / RESPONSABILE

Carlo La Vecchia lavecchia@marionegri.it 
RESEARCH GROUP MEMBERS / COMPONENTI DEL GRUPPO DI RICERCA

1 Eva Negri evanegri@marionegri.itEpidemiological Methodology Unit, Head
2 Alessandra Tavani tavani@marionegri.itChronic Disease Epidemiology Unit, Head
3 Fabio Parazzini parazzini@marionegri.itAnalytical Epidemiology Unit, Head
AFFILIATION / AFFILIAZIONE

Mario Negri Institute for Pharmacological Research Laboratory of General Epidemiology lavecchia@marionegri.itWEB
ADDRESS / INDIRIZZO

Via Eritrea, 62 21057 Milano
TELEPHONE / TELEFONO

+39.02.39014.1 (switchboard) +39.02.39014.527 (Laboratory of General Epidemiology)
FAX

+39.02.33200231
RESEARCH TOPICS / LINEE DI RICERCA

20 Epidemiology of several common cancers
20 Conduction and analysis of observational case-control studies
20 Conduction of meta-analysis and re-analysis of epidemiological studies of thyroid, breast and ovarian cancer.
COLLABORATIONS / COLLABORAZIONI

Harvard School of Public Health, Department of Epidemiology, Boston, USA  
Hôpital Necker - Enfants Malades, Centre of the Association Claude Bernard on Auto-immunes diseases, Paris, France  
International Agency for Research on Cancer, Unit of Field and Intervention Studies, Lyon, France  
International Epidemiology Institute, Rockville, USA  
National Cancer Institute, Environmental Studies Section, Bethesda, USA  
GRANTS / FINANZIAMENTI

Associazione Italiana per la Ricerca sul Cancro
Lega Italiana Lotta contro i tumori
European Commission
Ministero della Sanità
3M Italia
ADDITIONAL INFORMATION / INFORMAZIONI AGGIUNTIVE

Epidemiological Methodology Unit - The Laboratory of Epidemiology is involved in the epidemiology of several common cancers (including cancers of the breast, female genital tract, respiratory and digestive sites, prostate and urinary organs, lymphoid malignancies, melanoma, etc.) and of cardiovascular diseases, both through a descriptive and an analytical approach. Among the activities of descriptive epidemiology are the analysis of temporal trends and of geographical distribution of mortality from cancer, cardiovascular diseases, and other selected conditions, in Italy and Europe; and the analysis of trends in tobacco consumption in the Italian population, and the corresponding effects on the incidence and mortality from lung and other tobacco-related neoplasms. Chronic Disease Epidemiology Unit - The analytic epidemiology includes the conduction and analysis of observational case-control studies, aiming at identify and better quantify the association between genetic factors (family history), selected lifestyle habits (diet, tobacco, alcohol, etc,), use of exogenous hormones and exposure to various substances and the development of various forms of cancers and cardiovascular diseases. In particular, the Laboratory works on the analysis of dietary correlates of cancer and cardiovascular disease risk; quantification of health effects of tobacco smoking, alcohol consumption and implications for prevention; epidemiological studies on the risk related to oral contraceptive and hormone replacement therapy use; evaluation of the impact of screening in the early diagnosis and prevention of cancer. Analytical Epidemiology Unit - Other activities include the conduction of meta-analysis and re-analysis of epidemiological studies of thyroid, breast and ovarian cancer, and the analysis of historical cohort studies of occupational exposures to aromatic amines, asbestos, herbicides and other known potential carcinogens.
PUBLICATIONS 2001-2004 / PUBBLICAZIONI 2001-2004

1 Dal Maso L, Augustin L S A, Karalis A, Talamini R, Franceschi S, Trichopoulos D, Mantzoros C, La Vecchia C. (2004) Circulating adiponectin and endometrial cancer risk. J. Clin. Endocrinol. Metab. 89:1160-1163
2 Fernandez E, Gallus S, La Vecchia C, Talamini R, Negri E, Franceschi S. (2004) Family history and environmental risk factors for colon cancer. Cancer Epidemiol. Biomarkers Prev. 13:658-661
3 Levi F, Lucchini F, Negri E, Boyle P, La Vecchia C. (2004) Cancer mortality in Europe, 1995-1999, and an overview of trends since 1960. Int. J. Cancer 110:155-169
4 Bosetti C, Gallus S, Trichopoulou A, Talamini R, Franceschi S, Negri E, La Vecchia C. (2003) Influence of the mediterranean diet on the risk of cancers of the upper aerodigestive tract. Cancer Epidemiol. Biomarkers Prev. 12:1091-1094
5 Bosetti C, Talamini R, Franceschi S, Negri E, Garavello W, La Vecchia C. (2003) Aspirin use and cancers of the upper aerodigestive tract. Br. J. Cancer 88:672-674
6 Levi F, Lucchini F, Negri E, La Vecchia C. (2003) The end of the tobacco-related lung cancer epidemic in Europe. J. Natl. Cancer Inst. 95:631-632
7 Apolone G, Mosconi P, La Vecchia C.(2002) Post-traumatic stress disorder. N. Engl. J. Med. 346:1495-1496
8 La Vecchia C, Negri E, Pelucchi C, Franceschi S. (2002) Dietary folate and colorectal cancer. Int. J. Cancer 102: 545-547
9 La Vecchia C, Garattini S, Colombo P, Scarpino V. (2001) Attitudes towards smoking regulation in Italy. Lancet 358:245
10 Levi F, La Vecchia C, Boyle P, Lucchini F, Negri E. (2001) Western and eastern European trends in testicular cancer mortality. Lancet 357:1853-1854
LAST UPDATE / ULTIMO AGGIORNAMENTO DATI

March 21, 2005